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Endocrinology and Hormones

Endocrinology is the study of hormones, their receptors and intracellular signaling pathways, as well as the related diseases. The endocrine system functions can be broadly classified into several categories, including reproduction and sexual differentiation, development and growth, maintenance of the internal environment, and regulation of metabolism/nutrient supply.

There are three types of hormones based on their chemical composition: Amines (e.g. dopamine, adrenalin and noradrenalin); Steroids (e.g. estrogen, testosterone and glucocorticoids); Peptides (e.g. the peptide hormones insulin, ghrelin and vasopressin). Peptide hormones produced by secretory nervous tissue are known as neuropeptides. For example, thyroid hormone plays important parts in development, homeostasis and metabolism, while cortisol is essential for growth, nutrient supply and immune function. Moreover, the regulation of blood glucose involves several pancreatic peptide insulin and its counter regulatory hormone, glucagon, as well as cortisol, growth hormone and epinephrine.

Dysregulations in endocrine system are implicated in diseases such as Acromegaly, Cushing Syndrome, Diabetes, Dwarfism, Graves Disease, Hermaphroditism, Delayed and Precocious Puberty and Thyroid Diseases.

Items 1-10 of 202

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  1. Angiotensin 1/2 (1-7) amide
    Catalog No. :
    A1054
    Vasoconstrictor

    Angiotensin I/II (1-7) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide) is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse.

  2. Angiotensin 1/2 (2-7)
    Catalog No. :
    A1050
    Vasoconstrictor

    Angiotensin I/II (2-7) is a peptide (ARG-VAL-TYR-ILE-HIS-PRO) containing the amino acids 2-7 that are converted from Angiotensin I/II peptide.

  3. Angiotensin 1/2 (5-7)
    Catalog No. :
    A1049
    Vasoconstrictor

    Angiotensin 1/2 (5-7), (C17H27N5O4), a peptide with the sequence H2N-Ile-His-Pro-OH, MW=365.43.

  4. Angiotensin 1/2 (1-6)
    Catalog No. :
    A1048
    Vasoconstrictor

    Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) containing the amino acids 1-6 that are converted from Angiotensin I/II peptide.

  5. Angiotensin 1/2 (1-5)
    Catalog No. :
    A1047
    Vasoconstrictor

    Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) containing the amino acids 1-5 that are converted from Angiotensin I/II peptide.

  6. TRH Precursor Peptide
    Catalog No. :
    A1037
    Thyrotropin Releasing Hormone Precursor Peptide

    TRH Precursor Peptide

  7. Acetyl Angiotensinogen (1-14), porcine
    Catalog No. :
    A1034
    Angiotensinogen precursor

    Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21), a peptide with the sequenceAC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.05.

  8. a-MSH, amide
    Catalog No. :
    A1025
    Melanocyte-stimulating hormones
    a-MSH, amide (C77H109N21O19S1), a peptide with the sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, MW= 1664.9. The melanocyte-stimulating hormones (collectively referred to as MSH or intermedins) are a class of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland.
  9. Glucagon (19-29), human
    Catalog No. :
    A1019
    Potent Ca2+/Mg2+-ATPase inhibitor

    Glucagon(NH2-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-COOH), a peptide hormone secreted by the pancreas, raises blood glucose levels. Its effect is opposite that of insulin, which lowers blood glucose levels.

  10. Beta-Lipotropin (1-10), porcine
    Catalog No. :
    A1014
    Morphine-like substance

    Morphine-like substances exist in brain or the pituitary of various species. Beta-lipotropin (beta-LPH) was found to contain within its C-terminal sequence the primary structure of these peptides.

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