Endocrinology and Hormones
There are three types of hormones based on their chemical composition: Amines (e.g. dopamine, adrenalin and noradrenalin); Steroids (e.g. estrogen, testosterone and glucocorticoids); Peptides (e.g. the peptide hormones insulin, ghrelin and vasopressin). Peptide hormones produced by secretory nervous tissue are known as neuropeptides. For example, thyroid hormone plays important parts in development, homeostasis and metabolism, while cortisol is essential for growth, nutrient supply and immune function. Moreover, the regulation of blood glucose involves several pancreatic peptide insulin and its counter regulatory hormone, glucagon, as well as cortisol, growth hormone and epinephrine.
Dysregulations in endocrine system are implicated in diseases such as Acromegaly, Cushing Syndrome, Diabetes, Dwarfism, Graves Disease, Hermaphroditism, Delayed and Precocious Puberty and Thyroid Diseases.
- A1428 Fulvestrant (ICI 182,780)3 CitationSummary: Estrogen receptor antagonist, high affinity
- A5065 Bicalutamide1 CitationTarget: Androgen ReceptorsSummary: Androgen receptor antagonist
- A1659 DutasterideTarget: 5-alpha ReductasesSummary: 5-alpha-reductase inhibitor
- A1006 Angiotensin I (human, mouse, rat)Summary: Precursor of angiotensin II
- A1024 LEP (116-130) (mouse)Summary: An antiobesity hormone
- A1121 Melanocyte stimulating hormone release inhibiting factorSummary: MSH release-inhibiting factor
- A1055 Angiotensin 1/2 (1-8) amideSummary: Vasoconstrictor
- A1056 Angiotensin 1/2 + A (2 - 8)Summary: Vasoconstrictor
- A1084 parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]Summary: Enhancer of blood calcium level
- A1054 Angiotensin 1/2 (1-7) amideSummary: Vasoconstrictor