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E2 conjugating

E2 conjugating enzymes transfer the activated Ub/UBL (ubiquitin/ubiquitin-like proteins) from E1 enzymes to their activate cysteine site through thioester linkage. They then conjugate the E3 ligases to facilitate the attachment of Ub/UBL to the target proteins.

A8813 NSC697923

Target: Ub-conjugating enzyme (E2) complex

Summary: Inhibitor of E2 complex Ubc13-Uev1A,cell permeable and selective

insoluble in H2O; insoluble in EtOH; ≥26 mg/mL

E2 conjugating

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