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BTK

BTK (Bruton's tyrosine kinase) binds PIP3 and phosphorylates phospholipase C, plays a crucial role in B cell maturation as well as mast cell activation.

10 Items

per page
  1. RN486
    A8636 RN486
    Summary: Btk inhibitor,potent and selective
      ≥30.35 mg/mL
  2. CNX-774
    B1408 CNX-774
    Summary: BTK inhibitor, orally active, irreversible and selective
      Soluble in DMSO
  3. PCI-32765 Racemate
    B3242 PCI-32765 Racemate
    Summary: BTK inhibitor
      Soluble in DMSO
  4. Btk inhibitor 1 R enantiomer
    B3243 Btk inhibitor 1 R enantiomer
    Summary: Btk kinase inhibitor
      Soluble in DMSO
  5. LFM-A13
    B5952 LFM-A13
    Summary: BTK-specific tyrosine kinase inhibitor
      ≥36 mg/mL
  6. ONO-4059
    B5941 ONO-4059
    Summary: Highly potent and selective oral Btk inhibitor
      Soluble in DMSO
  7. ACP-196
    B6185 ACP-196
    Target: BTK
    Summary: irreversible BTK inhibitor
      ≥46.6 mg/mL
  8. PCI-32765 (Ibrutinib)
    A3001 PCI-32765 (Ibrutinib)
     4 Citation
    Summary: Bruton's tyrosine kinase (BTK) inhibitor
      ≥22.02 mg/mL
  9. AVL-292
    A3206 AVL-292
    Summary: Btk inhibitor
      ≥21.15 mg/mL
  10. CGI-1746
    A3302 CGI-1746
     1 Citation
    Target: BTK
    Summary: Btk inhibitor
      ≥29 mg/mL

10 Items

per page
Relate Categories
Specificity
  1. Selective2item
Reversibility
  1. Irreversible1 item
Target
  1. BTK2item
Reported Experiments
  1. Animal Experiments1 item