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BTK (Bruton's tyrosine kinase) binds PIP3 and phosphorylates phospholipase C, plays a crucial role in B cell maturation as well as mast cell activation.

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  1. ACP-196
    Catalog No. :
    irreversible BTK inhibitor
  2. ONO-4059
    Catalog No. :
    Highly potent and selective oral Btk inhibitor
  3. LFM-A13
    Catalog No. :
    BTK-specific tyrosine kinase inhibitor
  4. Btk inhibitor 1 R enantiomer
    Catalog No. :
    Btk kinase inhibitor
    Btk inhibitor 1 R enantiomer is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.
  5. PCI-32765 Racemate
    Catalog No. :
    BTK inhibitor
    PCI-32765 is an inhibitor of Bruton tyrosine kinase (BTK) with IC50 value of 0.5nM .
  6. CNX-774
    Catalog No. :
    BTK inhibitor, orally active, irreversible and selective
    CNX-774 is an irreversible, orally active, and highly selective BTK inhibitor with IC50 of <1 nM.
  7. RN486
    Catalog No. :
    Btk inhibitor,potent and selective
    RN486 is a reversible inhibitor of Btk with IC50 value of 4.0 nM [1].
  8. CGI-1746
    Catalog No. :
    Btk inhibitor
    CGI-1746 is a selective and potent inhibitor of Bruton's tyrosine kinase (BTK) with IC50 value of 1.9 nM [1][2].
  9. AVL-292
    Catalog No. :
    Btk inhibitor
    CC-292, formerly known as AVL-292, is an orally active, potent irreversible small molecule inhibitor of BTK with IC50 of 0.5 nM and EC50 of 8 nM.
  10. PCI-32765 (Ibrutinib)
    Catalog No. :
    Bruton's tyrosine kinase (BTK) inhibitor

    PCI-32765, also named as Ibrutinib, is a Bruton tyrosine kinase inhibitor which is used to study the biological effects of Bruton tyrosine kinase inhibition on mature B-cell function and the progression of B cell-associated diseases in vivo.

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