SRPK (serine/arginine-rich protein-specific kinases) specifically phosphorylate their substrate at serine residues in RS domain. It functions in SR splicing factors phosphorylation and splicing regulation. It is involvd in regulation of HBV replication, neuronal apoptosis and muscle development etc.
- SRPIN340Catalog No. :B2032Selective SRPK1 inhibitorSRPIN340 is a highly selective inhibitor of SR protein phosphorylation with a Ki value of 0.89μM for SRPK1 .