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Apoptosis Inducers

Apoptosis, a programmed cell death to eliminate damaged or abnormal cells, is a highly organized physiological process characterized by condensation of nuclear heterochromatin, cell shrinkage and loss of positional organization of organelles in the cytoplasm. Apoptosis inducers are a collection of compounds that are capable of inducing apoptosis in cells. Apoptosis has been extensively studied in numerous researches, where induction of apoptosis has been associated with a variety of events, including activation of p53 gene, transcription factor NF-κB or caspases. Apoptosis inducers have the potential to be incorporated into the management and therapy or prevention of cancer for their ability to induce apoptosis in cancer cells.

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  1. 7BIO
    Catalog No. :
    C5685
    caspase independent nonapoptotic cell death inducer
  2. F16
    Catalog No. :
    C5565
    potential antitumor agent
  3. ML-291
    Catalog No. :
    C5358
    apoptosis inducer
  4. Psoralidin
    Catalog No. :
    C4962
    apoptosis inducer
  5. (±)-Jasmonic Acid methyl ester
    Catalog No. :
    C4403
    suppresses proliferation and induces apoptosis
  6. 15-acetoxy Scirpenol
    Catalog No. :
    C4698
    mycotoxin that induce apoptotic cell death
  7. Destruxin B
    Catalog No. :
    C4423
    insecticidal and phytotoxic activity;induces apoptosis
  8. Citrinin
    Catalog No. :
    C3528
    mycotoxin that induces apoptosis and blocks tubulin polymerization as well as mitotic spindle assembly
  9. MPI-0441138
    Catalog No. :
    C3296
    inducer of apoptosis and growth inhibition
  10. Epibrassinolide
    Catalog No. :
    B4782
    Potential apoptosis inducer;steroidal plant growth stimulant
    Epibrassinolide (EBR; B1105; 24-Epibrassinolide) is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family; was shown as a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth.

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