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HMG-CoA Reductase

HMG-CoA Reductase (HMGR) catalyzes the rate-limiting step of the sterol and isoprenoid biosynthesis. It is required for normal cellular functions and a target for hypocholesterolemic drug.

Items 1-10 of 13

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  1. (3S,5S)-Atorvastatin (sodium salt)
    C4030 (3S,5S)-Atorvastatin (sodium salt)
    Summary: negetive control of Atorvastatin, HMG-CoA reductase inhibitor
      ≤0.5 mg/mL
  2. Simvastatin (sodium salt)
    C4426 Simvastatin (sodium salt)
    Summary: HMG-CoA reductase inhibitor
      ≥28.85 mg/mL
  3. Mevastatin
    B1788 Mevastatin
    Target: HMG-CoA Reductases
    Summary: HMG-CoA reductase inhibitor
      insoluble in H2O; ≥15.95 mg/mL
  4. Rosuvastatin
    B1123 Rosuvastatin
    Summary: Competitive inhibitor of HMG-CoA reductase
      ≥48.2 mg/mL
  5. Pitavastatin
    B1124 Pitavastatin
    Summary: HMG-CoA reductase inhibitor
      ≥10.56 mg/mL
  6. Pravastatin
    B1125 Pravastatin
    Summary: HMG-CoA reductase inhibitor against sterol synthesis
      ≥14.05 mg/mL
  7. Pitavastatin Calcium
    A8504 Pitavastatin Calcium
     1 Citation
    Target: HMG-CoA Reductases
    Summary: Enzyme HMGCR inhibitor
      ≥34.85 mg/mL
  8. Simvastatin (Zocor)
    A8522 Simvastatin (Zocor)
    Target: HMG-CoA Reductases
    Summary: HMGCR (HMG-CoA reductase) inhibitor
  9. Fluvastatin Sodium
    A4363 Fluvastatin Sodium
    Summary: HMG-CoA reductase inhibitor
  10. Lovastatin
    A4365 Lovastatin
    Target: HMG-CoA Reductases
    Summary: HMG-CoA reductase inhibitor

Items 1-10 of 13

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