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Spleen Tyrosine Kinase (Syk)

Syk is a family of non-receptor cytoplasmic tyrosine kinases that plays a role in transmitting signals from a variety of cell surface receptors including CD74, Fc Receptor, and integrins.

Items 1-10 of 12

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  1. BAY 61-3606
    A3227 BAY 61-3606
    Target: Syk
    Summary: Syk Inhibitor
      insoluble in H2O; insoluble in EtOH; ≥7.94 mg/mL
  2. BAY 61-3606 dihydrochloride
    A3228 BAY 61-3606 dihydrochloride
    Summary: Syk tyrosine kinase inhibitor
      Soluble in DMSO
  3. PRT062607 Hydrochloride
    A3736 PRT062607 Hydrochloride
     1 Citation
    Target: Syk
    Summary: SYK inhibitor,potent and selective
      ≥21.5 mg/mL
  4. GS-9973
    B3553 GS-9973
    Target: Syk
    Summary: Syk inhibitor, orally bioavailable and selective
      insoluble in EtOH; insoluble in H2O; ≥20.55 mg/mL
  5. Piceatannol
    N2031 Piceatannol
    Summary: p56lck/Syk inhibitor
      insoluble in H2O; ≥12.2 mg/mL
  6. RO9021
    B6158 RO9021
    Summary: Syk inhibitor
      Soluble in DMSO
  7. PRT-060318
    B6161 PRT-060318
    Summary: novel Syk inhibitor
      ≥45.7 mg/mL
  8. R406 (free base)
    A5880 R406 (free base)
    Summary: Syk inhibitor
      ≥23.5 mg/mL
  9. R788 disodium
    A8332 R788 disodium
    Target: Syk
    Summary: Syk inhibitor,ATP competitive and potent
      ≥62.4 mg/mL
  10. R406
    A8546 R406
     1 Citation
    Target: Syk
    Summary: SYK inhibitor,potent and ATP-competitive
      ≥31.45 mg/mL

Items 1-10 of 12

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