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IGF1R

IGF1R (insulin-Like growth factor 1 receptor) is a receptor tyrosine kinase that bind to insulin-like growth factor 1 with high affinity. It plays a vital role in in cell growth, cell survival and malignant transformation etc.

9 Items

per page
  1. AXL1717
    A3209 AXL1717
    Target: Insulin-like growth factor receptors(IGFRs)
    Summary: IGF-1R inhibitor,orally active
      ≥20.7 mg/mL
  2. NT157
    B7808 NT157
     1 Citation
    Summary: IRS-1/2 inhibitor, inhibits IGF-1R and STAT3 signaling pathway
  3. AG-1024
    A2673 AG-1024
    Summary: Selective IGF-1R inhibitor
  4. BMS-754807
    A1185 BMS-754807
    Target: Insulin and Insulin-like Receptors
    Summary: IGF-1R/InsR inhibitor,potent and selective
      ≥23.05 mg/mL
  5. GSK1904529A
    A1302 GSK1904529A
    Target: Insulin and Insulin-like Receptors
    Summary: Selective IGF-1R/IR inhibitor
      ≥42.6 mg/mL
  6. NVP-AEW541
    A2278 NVP-AEW541
    Target: Insulin Receptor
    Summary: IGF-IR inhibitor, novel, potent and selective
      ≥22 mg/mL
  7. PQ 401
    A2033 PQ 401
     1 Citation
    Summary: IGF1R inhibitor,potent and cell-permeable
      insoluble in H2O; ≥17.1 mg/mL
  8. Linsitinib
    A8334 Linsitinib
     3 Citation
    Summary: IGF1R/IR inhibitor,potent and novel
      ≥21.08 mg/mL
  9. NVP-ADW742
    B1584 NVP-ADW742
    Summary: Selective IGF-1R inhibitor
      Soluble in DMSO

9 Items

per page