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PLK

PLK (Polo-like kinase 1) is a serine/threonine-protein that are implicated in cell cycle, mitosis, cytokinesis and DNA damage etc.

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  1. BI 2536
    A3965 BI 2536
     1 Citation
    Target: PLK|Bromodomain-containing proteins(BRDs)
    Summary: Plk1 inhibitor,potent and ATP-competitive
      insoluble in H2O; ≥13.04 mg/mL
  2. Rigosertib sodium salt
    A1404 Rigosertib sodium salt
     1 Citation
    Target: PLK
    Summary: Plk1 inhibitor
      ≥23.65 mg/mL
  3. HMN-214
    A5413 HMN-214
    Summary: Plk inhibitor,broad-spectrum anti-tumor agent
      ≥21.2 mg/mL
  4. GSK461364
    A8441 GSK461364
     3 Citation
    Target: PLK
    Summary: Plk1 inhibitor
  5. BI6727 (Volasertib)
    A8558 BI6727 (Volasertib)
     1 Citation
    Summary: Plk inhibitor,highly potent
      insoluble in H2O; ≥10.31 mg/mL
  6. MLN0905
    A8680 MLN0905
    Target: PLK
    Summary: Potent PLK1 inhibitor
      ≥24.35 mg/mL
  7. Ro3280
    A8681 Ro3280
    Target: PLK
    Summary: PLK1 inhibitor,potent and highly selective
      ≥27.2 mg/mL
  8. Rigosertib
    B1288 Rigosertib
    Target: PI3K|PLK
    Summary: PI3K/PLK1 inhibitor
      Soluble in DMSO
  9. SBE 13 HCl
    B5857 SBE 13 HCl
    Target: PLK
    Summary: Inactive Plk1 inhibitor
      Soluble in DMSO
  10. TAK960
    B5860 TAK960
    Target: PLK
    Summary: Oral and selective PLK1 inhibitor
      ≥28.05 mg/mL

Items 1-10 of 18

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