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FGFR

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

Relate Categories
Category
  • ALK 21items
  • Ack1 1item
  • Axl 6items
  • BMX Kinase 1item
  • Bcr-Abl 20items
  • Broad Spectrum Protein Kinase Inhibitor 9items
  • CSF-1R 3items
  • DDR1/DDR2 Receptor 1item
  • EGFR 69items
  • EphB4 1item
  • FAK 10items
  • FGFR 17items
  • FLT3 19items
  • HER2 15items
  • IGF1R 10items
  • IRAK 6items
  • ITK 1item
  • Insulin Receptor 6items
  • LRRK2 9items
  • Lck 1item
  • PDGFR 24items
  • PTKs/RTKs 3items
  • Pyk2 3items
  • ROR 6items
  • Spleen Tyrosine Kinase (Syk) 12items
  • Src 23items
  • Tie-2 2items
  • Trk 12items
  • VEGFR 56items
  • c-FMS 2items
  • c-Kit 7items
  • c-MET 25items
  • c-RET 7items
Specificity
  1. Selective 8 items
Reversibility
  1. Irreversible 1 item
Target
  1. Aurora Kinases 1 item
  2. CSF-1R 1 item
  3. FLT3 1 item
  4. VEGFR 6 items
  5. PDGFR 4 items
  6. c-Kit 2 items
  7. Bcr-Abl 1 item
  8. FGFR 9 items
  9. Src 1 item
  10. Tie-2 1 item
  11. RSK 1 item
  12. p70 S6K 1 item
Reported Experiments
  1. Animal Experiments 10 items
  2. Cell Experiments 4 items
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Bladder Cancer 2 items
  4. Breast Cancer 2 items
  5. Cancer 9 items
  6. Clear Cell Renal Cell Carcinoma 1 item
  7. Colorectal Cancer 2 items
  8. Lung Cancer 1 item
  9. Multiple Myeloma 4 items
  10. Ovarian Cancer 1 item