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FGFR

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

Items 1-10 of 16

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  1. Danusertib (PHA-739358)
    A4116 Danusertib (PHA-739358)
     2 Citation
    Target: Aurora Kinases
    Summary: Pan-aurora kinase inhibitor
      ≥23.75 mg/mL
  2. E-3810
    A3378 E-3810
    Summary: VEGF/FGF dual inhibitor, potent and selective
      Soluble in DMSO
  3. LY2874455
    A3576 LY2874455
    Summary: FGF/FGFR Inhibitor
      ≥44.4 mg/mL
  4. NVP-BGJ398 phosphate
    A3673 NVP-BGJ398 phosphate
    Summary: FGFR inhibitor
      insoluble in EtOH; ≥28.07 mg/mL
  5. ACTB-1003
    B4904 ACTB-1003
    Target: VEGFR|FGFR|Tie-2|RSK|p70 S6K
    Summary: FGFR1 inhibitor
      insoluble in H2O; ≥18.15 mg/mL
  6. BLU9931
    A8706 BLU9931
    Target: FGFR
    Summary: FGFR4 inhibitor,potent and irreversible
      ≥50.9 mg/mL
  7. CH5183284 (Debio-1347)
    B4985 CH5183284 (Debio-1347)
    Summary: selective and orally available FGFR inhibitor
      ≥35.6 mg/mL
  8. PD 161570
    B7486 PD 161570
    Summary: FGFR inhibitor
      <53.25 mg/mL
  9. BGJ398
    A3014 BGJ398
     1 Citation
    Target: FGFR
    Summary: FGFR inhibitor ,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥7 mg/mL
  10. Pazopanib (GW-786034)
    A3022 Pazopanib (GW-786034)
    Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥10.95 mg/mL

Items 1-10 of 16

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