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FGFR

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

Items 1-10 of 16

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  1. BGJ398
    A3014 BGJ398
     1 Citation
    Target: FGFR
    Summary: FGFR inhibitor ,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥7 mg/mL
  2. Pazopanib (GW-786034)
    A3022 Pazopanib (GW-786034)
    Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥10.95 mg/mL
  3. Danusertib (PHA-739358)
    A4116 Danusertib (PHA-739358)
     2 Citation
    Target: Aurora Kinases
    Summary: Pan-aurora kinase inhibitor
      ≥23.75 mg/mL
  4. E-3810
    A3378 E-3810
    Summary: VEGF/FGF dual inhibitor, potent and selective
      Soluble in DMSO
  5. LY2874455
    A3576 LY2874455
    Summary: FGF/FGFR Inhibitor
      ≥44.4 mg/mL
  6. NVP-BGJ398 phosphate
    A3673 NVP-BGJ398 phosphate
    Summary: FGFR inhibitor
      insoluble in EtOH; ≥28.07 mg/mL
  7. SKLB610
    A8237 SKLB610
    Summary: Potent VEGFR inhibitor
      insoluble in H2O; ≥20.75 mg/mL
  8. Nintedanib (BIBF 1120)
    A8252 Nintedanib (BIBF 1120)
     3 Citation
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
  9. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  10. Ponatinib (AP24534)
    A5467 Ponatinib (AP24534)
     1 Citation
    Target: VEGFR|PDGFR|Bcr-Abl|FGFR|Src
    Summary: pan-BCR-ABL inhibitor,multi-kinase inhibitor
      ≥53.3 mg/mL

Items 1-10 of 16

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