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FGFR

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

Items 1-10 of 16

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  1. SKLB610
    A8237 SKLB610
    Summary: Potent VEGFR inhibitor
      insoluble in H2O; ≥20.75 mg/mL
  2. Nintedanib (BIBF 1120)
    A8252 Nintedanib (BIBF 1120)
     3 Citation
    Target: VEGFR|PDGFR|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
  3. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  4. Ponatinib (AP24534)
    A5467 Ponatinib (AP24534)
     1 Citation
    Target: VEGFR|PDGFR|Bcr-Abl|FGFR|Src
    Summary: pan-BCR-ABL inhibitor,multi-kinase inhibitor
      ≥53.3 mg/mL
  5. ALK-IN-1
    A1367 ALK-IN-1
    Summary: Anaplastic lymphoma kinase (ALK) inhibitor
      ≥26.45 mg/mL
  6. AZD4547
    A8350 AZD4547
    Target: FGFR
    Summary: FGFR inhibitor
      ≥23.2 mg/mL
  7. ACTB-1003
    B4904 ACTB-1003
    Target: VEGFR|FGFR|Tie-2|RSK|p70 S6K
    Summary: FGFR1 inhibitor
      insoluble in H2O; ≥18.15 mg/mL
  8. BLU9931
    A8706 BLU9931
    Target: FGFR
    Summary: FGFR4 inhibitor,potent and irreversible
      ≥50.9 mg/mL
  9. CH5183284 (Debio-1347)
    B4985 CH5183284 (Debio-1347)
    Summary: selective and orally available FGFR inhibitor
      ≥35.6 mg/mL
  10. PD 161570
    B7486 PD 161570
    Summary: FGFR inhibitor
      <53.25 mg/mL

Items 1-10 of 16

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