MPS1 (monopolar spindle 1 kinase) is a crucial part of the spindle assembly checkpoint. It facilitates the formation of C-MAD2 (closed MAD2) conformer and the MCC (mitotic checkpoint complex) assembly, and involved in the tumor growth.
- Mps1-IN-1Catalog No. :B4907Mps1 kinase inhibitor
- Mps1-IN-2Catalog No. :B1138Mps1 kinase inhibitorMps1-IN-2 is a potent and selective ATP-competitive inhibitor of Mps1 kinase with the IC50 value of 145nM .
- AZ3146Catalog No. :A8372Mps1 inhibitor,potent and selectiveAZ3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM).