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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

A3967 Lapatinib Ditosylate

Target: EGFR|ErbB-2

Summary: EGFR/HER2 inhibitor,potent and selective

≥24.3 mg/mL
A8218 Lapatinib
2 Citation

Target: ErbB

Summary: EGFR/HER2 inhibitor,potent,selective and reversible

≥29.05 mg/mL
A8219 Gefitinib (ZD1839)
3 Citation

Target: EGFR

Summary: Selective EGFR inhibitor

≥22.34 mg/mL
A8234 Erlotinib Hydrochloride
2 Citation

Summary: Selective EGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥6.44 mg/mL
A8247 Afatinib (BIBW2992)
1 Citation

Target: EGFR

Summary: Irreversible EGFR/HER2 inhibitor

≥24.3 mg/mL
A1389 WZ4002

Summary: Mutant-selective EGFR inhibitor(L858R,T790M), irreversible and potent

≥24.7 mg/mL
A2412 CP-724714

Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1R

Summary: HER2 inhibitor,potent and selective

≥23.5 mg/mL
A1835 Pelitinib (EKB-569)

Summary: EGFR inhibitor,potent and irreversible

insoluble in EtOH; insoluble in H2O; ≥11.7 mg/mL
A1393 WZ8040

Target: EGFR

Summary: EGFR T790M inhibitor,irreversible amd potent

≥24.05 mg/mL
A2822 AC480 (BMS-599626)

Target: EGFR

Summary: HER1/2 inhibitor,selective and efficacious

≥28.35 mg/mL