Hedgehog
Hh (Hedgehog) signalling is a evolutionarily conserved pathway that is critical for embryonic development, tissue and organ morphogenesis. Mammalian Hh protein ligands include Sonic Hh, Desert Hh and Indian Hh. Dysfunctions of Hh singalling lead to developmental abnormalities and cancer.
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C5138 CUR 61414Summary: potent inhibitor of hedgehog-induced cellular activity -
C5136 Oxy-16Summary: antagonist of hedgehog activity -
B7803 MK-4101Summary: Hedgehog (Hh) signaling pathway inhibitor -
B5837 SAGSummary: Hh and Smo agonist -
B7669 20(S)-HydroxycholesterolSummary: Allosteric activator of the Hedgehog signaling pathway Smoothened (Smo) oncoprotein -
B6812 U 18666ASummary: inhibitor of cholesterol transport and synthesis -
A8659 SANT-11 CitationSummary: Shh inhibitor,potent and cell-permeable -
A8658 AY 9944 dihydrochlorideSummary: Hedgehog Inhibitor -
A8656 JervineSummary: Hedgehog signaling Inhibitor -
A8655 Ciliobrevin ASummary: Hh pathway antagonist