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Topoisomerase

Topoisomerase are enzymes that regulate the overwinding or underwinding of DNA.

Items 31-38 of 38

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  1. DOXO-EMCH
    A3372 DOXO-EMCH
    Summary: Prodrug of doxorubicin
      Soluble in DMSO
  2. Genz-644282
    A3434 Genz-644282
    Summary: Non-camptothecin inhibitor of topoisomerase I
      Soluble in DMSO
  3. TH-302
    A3872 TH-302
    Summary: Hypoxia-activated prodrug,inhibits H460/HT29 cell growth
      ≥22.45 mg/mL
  4. Voreloxin
    A3924 Voreloxin
    Summary: Topo II inhibitor
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  5. Voreloxin Hydrochloride
    A3925 Voreloxin Hydrochloride
    Summary: Antineoplastic naphthyridine analogue
      Soluble in DMSO
  6. Luotonin A
    C4433 Luotonin A
    Summary: binds to and stabilizes the topoisomerase I-DNA binary complex
      ≤3 mg/mL
  7. UK 1
    C5006 UK 1
    Summary: inhibitor of topoisomerase II and hepatitis C viral replication
      Soluble in DMSO;Soluble in dimethyl formamide
  8. 9-amino Camptothecin
    C5790 9-amino Camptothecin
    Summary: topoisomerase I inhibitor
      ≤1 mg/mL

Items 31-38 of 38

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