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Topoisomerase

Topoisomerase are enzymes that regulate the overwinding or underwinding of DNA.

Items 11-20 of 38

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  1. Irinotecan
    A5133 Irinotecan
    Summary: Topoisomerase I inhibitor
      insoluble in H2O; ≥11.4 mg/mL
  2. Dexrazoxane HCl (ICRF-187, ADR-529)
    A1602 Dexrazoxane HCl (ICRF-187, ADR-529)
    Target: Topoisomerases
    Summary: Topoisomerase II inhibitor,intracellular ion chelator,cardioprotective agent
      insoluble in EtOH; ≥15.24 mg/mL
  3. Moxifloxacin HCl
    A5323 Moxifloxacin HCl
     1 Citation
    Target: Antibiotic
    Summary: Fluoroquinolone antibiotic
      insoluble in EtOH; ≥43.91 mg/mL
  4. Ofloxacin
    A5511 Ofloxacin
    Target: Topoisomerases|DNA gyrase
    Summary: Fluoroquinolones,antibiotics
      insoluble in H2O; insoluble in EtOH; ≥12.03 mg/mL
  5. Teniposide
    A8532 Teniposide
    Summary: Topoisomerase inhibitor
      ≥23.65 mg/mL
  6. Beta-Lapachone
    B2290 Beta-Lapachone
    Target: Topoisomerases
    Summary: DNA topoisomerase I inhibitor,selective
      insoluble in H2O; ≥10.85 mg/mL
  7. Amsacrine
    B1302 Amsacrine
    Summary: Topoisomerase 2 inhibitor
      ≥26.5 mg/mL
  8. Amsacrine hydrochloride
    B1303 Amsacrine hydrochloride
    Summary: Topoisomerase 2 inhibitor
      ≥55.56 mg/mL
  9. (S)-10-Hydroxycamptothecin
    B4745 (S)-10-Hydroxycamptothecin
    Target: Topoisomerases
    Summary: inhibitor of topoisomerase I
      ≥23.8 mg/mL
  10. Topotecan
    B4982 Topotecan
     1 Citation
    Summary: Topoisomerase 1 inhibitor
      ≥21.1 mg/mL

Items 11-20 of 38

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