In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
In one study where this peptide was labeled with 125I, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. The integrin alpha(IIb)beta(3)-specific cyclic hexapeptide contains an Arg-Gly-Asp (RGD) sequence.
2. Lim C, Moon J, et al. "Cyclic RGD-conjugated Pluronic(®) blending system for active, targeted drug delivery." Int J Nanomedicine. 2018 Aug 10;13:4627-4639. PMID:30127610
3. Schneider G, Suszynska M, Kakar S, et al. "Vitronectin in the Ascites of Human Ovarian Carcinoma Acts as a Potent Chemoattractant for Ovarian Carcinoma: Implication for Metastasis by Cancer Stem Cells[J]." Journal of Cancer Stem Cell Research, 2016, 4: e1005.
|Storage||Store at -20°C|
|Solubility||≥30.185mg/mL in DMSO, <2.59 mg/mL in EtOH, ≥59.2 mg/mL in H2O|
|Chemical Name||2-[(2S,5R,8S,11S)-8-(4-aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid|
|Shipping Condition||Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.|
|Description||Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin.|
Quality Control & MSDS
- View current batch:
Purity = 98.11%
- COA (Certificate Of Analysis)
- MS (Mass Spectrometry)
- NMR (Nuclear Magnetic Resonance)
- MSDS (Material Safety Data Sheet)