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α-Amanitin

Catalog No.
A4548
Inhibitor of RNA polymerase II.
Grouped product items
SizePriceStock Qty
1mg
$231.00
Ship with 5-10 days

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Background

Inhibitor of RNA polymerase II. Inhibits transcription in eukaryotic cells. Binds and blocks the largest subunits of RNA polymerase II, preventing new ribonucleotides from incorporating into the nascent RNA chain. Potent amatoxin.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt918.97
Cas No.23109-05-9
FormulaC39H54N10O14S
SolubilitySoluble in Ethanol
SDFDownload SDF
Canonical SMILESCCC(C)C1C(=O)NCC(=O)NC2CS(=O)C3=C(CC(C(=O)NCC(=O)N1)NC(=O)C(NC(=O)C4CC(CN4C(=O)C(NC2=O)CC(=O)N)O)C(C)C(CO)O)C5=C(N3)C=C(C=C5)O
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

α-Amanitin