Anti-p63 Rabbit Polyclonal Antibody
Catalog No.
PA1262
Anti-p63 Rabbit Polyclonal Antibody
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Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis.
8626
EEC3; KET; LMS; SHFM4; TA p63 alpha; TP63; p51; p73H; p73L; tumor protein p63
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 77 kDa; Observed MW: 77 kDa
Unmodified
IgG
Polyclonal Antibody
Liquid
See label
Carrier Free
A synthesized peptide derived from human p63
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.