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Heat shock proteins (HSPs) are a family of highly conserved proteins that are expressed, either constitutively or regulated inductively, in response to a wide range of physiological and environmental insults, such as heat shock. According to molecular weight, mammalian HSPs are classified into four subfamilies, including HSP90 (90 kDa), HSP70 (70 kDa), HSP60 (60 kDa) and small HSPs (15 to 30 kDa), among which HSP90 and HSP70 are two of the most studied stress-inducible HSPs. HSP90 is a highly abundant chaperone protein characterized by containing three relevant domains, including the N-terminal domain, the charged middle linker region and the C-terminal dimerization domain; while HSP70 is an ATP-dependent chaperone protein characterized by containing two distinct functional domains, including a peptide binding domain (PBD) and the amino-terminal ATPase domain (ABD). Collectively HSPs play a fundamental role in maintaining the stability of other cellular proteins.

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  1. Cat.No. Product Name Information
  2. T1118 HSP90 Antibody (78T3) Monoclonal HSP90 antibody, reacts with total HSP90 protein
  3. T1119 HSP90 Antibody Polyclonal HSP90 antibody, reacts with total HSP90 protein
  4. T1120 HSP90 Antibody (G28) Polyclonal HSP90 antibody, reacts with total HSP90 protein
  5. T1207 Phospho-HSP90α (Thr5/7) Antibody Polyclonal Phospho-HSP90α (Thr5/7) antibody, reacts with HSP90α protein phosphorylated at Thr5/7


  1. Cat.No. Product Name Information
  2. A3161 Alvespimycin Hsp90 inhibitor,potent and selective
  3. A3739 PU-H71 Hsp90 inhibitor,potent and selective
  4. A3756 Retaspimycin HSP90 inhibitor,antiproliferative and antineoplastic
  5. A2213 17-DMAG (Alvespimycin) HCl Hsp90 inhibitor
  6. A4068 SNX-2112 Hsp90 inhibitor,ATP-competitve,potent and selective
  7. A4065 PF-04929113 (SNX-5422) Hsp90 inhibitor,potent and selective
  8. A4064 NVP-BEP800 Oral Hsp90β inhibitor, novel, fully synthetic
  9. A4062 KW-2478 Potent Hsp90 inhibitor, novel, non-ansamycin,
  10. A4061 IPI-504 (Retaspimycin hydrochloride) Hsp90 inhibitor,novel, potent,selective
  11. A4060 Geldanamycin Hsp90 inhibitor,potent and specific
  12. A4058 BIIB021 Hsp90 inhibitor,selective and competitive
  13. A4057 AUY922 (NVP-AUY922) Top Seller Potent Hsp90 inhibitor
  14. A4056 AT13387 Hsp90 inhibitor
  15. A4054 17-AAG (KOS953) Top Seller Hsp90 inhibitor
  16. A3109 17-AAG Hydrochloride Hsp90 inhibitor,geldanamycin analogue
  17. A4388 XL-888 Hsp90 inhibitor
  18. A4387 VER 155008 HSP 70 inhibitor,adenosine-derived
  19. A4386 Elesclomol (STA-4783) Oxidative stress/apoptosis inducer,potent and novel
  20. A4385 Ganetespib (STA-9090) Top Seller Hsp90 inhibitor,non-geldanamycin
  21. B4571 CH5138303 CH5138303 is an inhibitor of Hsp90 with Kd value of 0.48 nM [1].
  22. A4063 MPC-3100 Hsp90 inhibitor
  23. A4067 Radicicol ATPase/kinase inhibitor
  24. B3592 VER-50589 VER-50589 is a potent inhibitor of HSP90 with IC50 value of 21 nM for HSP90β [1].
  25. B3593 VER-49009 VER-49009 is a potent and selective inhibitor of HSP90 with IC50 value of 47 nM for HSP90β [1]
  26. B3693 NMS-E973 Hsp90 inhibitor,potent and selective