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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

Items 51-60 of 62

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  1. GDC-0941 dimethanesulfonate
    A3432 GDC-0941 dimethanesulfonate
    Summary: PI3K inhibitor
      insoluble in H2O; insoluble in EtOH; ≥207.6 mg/mL
  2. NVP-BKM120 Hydrochloride
    A3674 NVP-BKM120 Hydrochloride
    Summary: PI3K inhibitor
      ≥44.7 mg/mL
  3. PI-103 Hydrochloride
    A3724 PI-103 Hydrochloride
    Target: PI3K|mTOR|DNA-PK
    Summary: DNA-PK/PI 3-kinase/mTOR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.25 mg/mL
  4. VS-5584 (SB2343)
    A3927 VS-5584 (SB2343)
    Target: PI3K|mTOR
    Summary: MTOR/P13K inhibitor,potent and selective
      insoluble in H2O; ≥17.7 mg/mL
  5. GDC-0084
    B7826 GDC-0084
    Summary: PI3K and mTOR inhibitor, brain-permeable
      insoluble in H2O; insoluble in EtOH; ≥2.83 mg/mL
  6. LY3023414
    B6099 LY3023414
    Target: Akt|PI3K|mTOR|DNA-PK
    Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor
      ≥40.6 mg/mL
  7. GSK2292767
    B6173 GSK2292767
    Summary: PI3Kδ inhibitor,potent and selective
      Soluble in DMSO
  8. AZD8835
    B6178 AZD8835
    Summary: PI3Kα and PI3Kδ inhibitor
      Soluble in DMSO
  9. PX 866
    C3271 PX 866
    Summary: PI3K inhibitor
      ≤25 mg/mL
  10. INK1117
    C3103 INK1117
    Summary: PI3Kα inhibitor
      ≤1 mg/mL

Items 51-60 of 62

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