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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

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  1. GDC-0084
    B7826 GDC-0084
    Summary: PI3K and mTOR inhibitor, brain-permeable
      insoluble in H2O; insoluble in EtOH; ≥2.83 mg/mL
  2. PI 828
    B7198 PI 828
    Summary: PI 3-Kinase inhibitor
      Soluble in DMSO
  3. HS-173
    B4492 HS-173
    Target: PI3K
    Summary: novel PI3K inhibitor
      ≥21.1 mg/mL
  4. LY3023414
    B6099 LY3023414
    Target: Akt|PI3K|mTOR|DNA-PK
    Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor
      ≥40.6 mg/mL
  5. GSK2269557
    C5012 GSK2269557
    Summary: inhibitor of PI3Kδ
      ≤0.2 mg/mL
  6. BAY 80-6946 (Copanlisib)
    B2178 BAY 80-6946 (Copanlisib)
     1 Citation
    Target: PI3K
    Summary: PI3K inhibitor
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  7. CH5132799
    B2183 CH5132799
    Summary: Class I PI3K inhibitor
      Soluble in DMSO
  8. AS-252424
    B2180 AS-252424
    Target: Akt|PI3K
    Summary: PI3Kγ inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥30.5 mg/mL
  9. PIK-293
    B2187 PIK-293
    Summary: PI3K inhibitor
      Soluble in DMSO
  10. PIK-294
    B2188 PIK-294
    Summary: highly selective p110δ inhibitor
      ≥24.5 mg/mL

Items 21-30 of 62

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