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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

Items 11-20 of 62

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  1. Quercetin dihydrate
    A2552 Quercetin dihydrate
    Target: PI3K|PIM1 kinase|phospholipase A2
    Summary: PLA2 and PI 3-kinase inhibitor
      ≥33.8 mg/mL
  2. PIK-75 HCl
    A2080 PIK-75 HCl
    Summary: Inhibitor of PI3K isoform p110α
      insoluble in H2O; insoluble in EtOH; ≥8.15 mg/mL
  3. IC-87114
    A2065 IC-87114
    Summary: PI3Kδ inhibitor
  4. AS-605240
    A5176 AS-605240
    Target: PI3K
    Summary: Potent and selective PI 3-Kγ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥4.28 mg/mL
  5. AZD6482
    A5478 AZD6482
    Target: PI3K
    Summary: PI3Kβ inhibitor,potent and selective
      insoluble in H2O; ≥20.4 mg/mL
  6. SAR245409 (XL765)
    A5634 SAR245409 (XL765)
    Summary: mTOR/PI3K inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15 mg/mL
  7. BYL-719
    A8346 BYL-719
     1 Citation
    Target: PI3K
    Summary: Selective PI3Kα inhibitor
      ≥22.07 mg/mL
  8. PF-04691502
    A8499 PF-04691502
    Target: Akt|PI3K|mTOR
    Summary: PI3K/mTOR (FRAP) inhibitor
      insoluble in H2O; insoluble in EtOH; ≥10.63 mg/mL
  9. PKI-402
    A8505 PKI-402
    Summary: PI3K inhibitor,selective, reversible and ATP-competitive
      insoluble in EtOH; insoluble in H2O; ≥14.28 mg/mL
  10. PP121
    B2172 PP121
    Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck
    Summary: Dual inhibitor of tyrosine and phosphoinositide kinases

Items 11-20 of 62

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