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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

Items 41-50 of 62

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  1. BAY 80-6946 (Copanlisib)
    B2178 BAY 80-6946 (Copanlisib)
     1 Citation
    Target: PI3K
    Summary: PI3K inhibitor
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  2. CH5132799
    B2183 CH5132799
    Summary: Class I PI3K inhibitor
      Soluble in DMSO
  3. AS-252424
    B2180 AS-252424
    Target: Akt|PI3K
    Summary: PI3Kγ inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥30.5 mg/mL
  4. AS-604850
    B2181 AS-604850
    Summary: PI3Kγ inhibitor,selective and ATP-competitve
      Soluble in DMSO
  5. PIK-293
    B2187 PIK-293
    Summary: PI3K inhibitor
      Soluble in DMSO
  6. PIK-294
    B2188 PIK-294
    Summary: highly selective p110δ inhibitor
      ≥24.5 mg/mL
  7. TG100713
    B2177 TG100713
    Target: PI3K
    Summary: pan-PI3K inhibitor
      soluble in DMSO
  8. CAY10505
    B2182 CAY10505
    Summary: Potent PI3Kγ inhibitor
      insoluble in EtOH; insoluble in H2O; ≥14.45 mg/mL
  9. GSK1059615
    B2176 GSK1059615
    Target: PI3K|mTOR
    Summary: PI3K and mTOR inhibitor,potent and reversible
      insoluble in EtOH; insoluble in H2O; ≥8.33 mg/mL
  10. CAL-101 (Idelalisib, GS-1101)
    A3005 CAL-101 (Idelalisib, GS-1101)
     2 Citation
    Target: PI3K
    Summary: PI3K inhibitor

Items 41-50 of 62

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