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MEK1/2

MEK1/2, also known as MAPKK (mitogen-activated protein kinase kinase), is a kinase enzyme which phosphorylates MAPK (mitogen-activated protein kinase).

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  1. PD 184161
    C4361 PD 184161
    Summary: MEK1/2 inhibitor
      ≤10 mg/mL
  2. Refametinib
    B1267 Refametinib
    Target: MEK
    Summary: MEK 1/ MEK 2 inhibitor
      insoluble in H2O; ≥151.8 mg/mL
  3. GDC-0623
    B1135 GDC-0623
    Target: MEK
    Summary: MEK1 inhibitor, potent and ATP-uncompetitive
      insoluble in H2O; ≥16.85 mg/mL
  4. U0124
    B6882 U0124
    Summary: Inactive analog of U0126(MEK-1/2 inhibitor), used as a negative control
      <22.63 mg/mL
  5. PD 198306
    B7124 PD 198306
    Summary: MEK1/2 inhibitor
      Soluble in DMSO
  6. 10Z-Hymenialdisine
    B5126 10Z-Hymenialdisine
    Summary: Pan kinase inhibitor
      Soluble in DMSO
  7. Arctigenin
    N2399 Arctigenin
    Summary: Anti-inflammatory, antiproliferative
      insoluble in H2O; insoluble in EtOH; ≥17.2 mg/mL

Items 31-37 of 37

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