Cobimetinib (R-enantiomer)
Catalog No.
A3323
Selective MEK inhibitor
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GDC-0973(XL-518) is a selective inhibitor of MEK. GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors.
| Storage | Store at -20°C |
| M.Wt | 531.31 |
| Cas No. | 934660-94-3 |
| Formula | C21H21F3IN3O2 |
| Synonyms | GDC-0973 R-enantiomer;XL-518 R-enantiomer |
| Solubility | Soluble in DMSO |
| Chemical Name | [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2R)-piperidin-2-yl]azetidin-1-yl]methanone |
| SDF | Download SDF |
| Canonical SMILES | C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
