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HCV Protease

Hepatitis C virus (HCV) protease is an enzyme, either viral or cellular, that catalyzes the hydrolysis of the long polyprotein precursor (approximately 3000 amino acids) encoded by HCV genome into at least ten individual proteins, including four structural proteins (C, E1, E2 and p7) and six nonstructural (NS) proteins (NS2, NS3, NS4A, NS4B, NS5A and NS5B). The commonly studied HCV proteases are two virally encode proteases involved in the viral replication of HCV, including HCV NS2/3 protease, a highly hydrophobic protease responsible for the cleavage of NS2 and NS3, and HCV NS3-4A serine protease, a covalent heterodimer responsible for cleavage at four sites of the HCV polyprotein.

Compare Products

  1. Cat.No. Product Name Information
  2. A3182 Anguizole Inhibitor of HCV replication
  3. A3195 Asunaprevir (BMS-650032) NS3 protease inhibitor
  4. A3217 Balapiravir Polymerase inhibitor,anti-HCV
  5. A3257 BMS-790052 dihydrochloride HCV NS5A inhibitor
  6. A3261 Boceprevir HCV protease inhibitor,potent and selective
  7. A5618 Daclatasvir (BMS-790052) HCV NS5A inhibitor
  8. A4024 Danoprevir (RG7227) HCV NS3/4A protease inhibitor
  9. A8898 HZ-1157 HCV NS3/4A protease inhibitor
  10. A3643 Narlaprevir HCV NS3 protease inhibitor
  11. A3655 Nesbuvir NS5B polymerase inhibitor

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