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Protease Inhibitor Cocktail(MS-SAFE, 50X in DMSO)

Catalog No.
K4001
Mass spectrometry (MS)-compatible protease inhibitor Cocktail
Grouped product items
SizePriceStock Qty
1ml
$50.00
In stock
5x1ml
$183.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Product Citation

Description

Crude cell extracts contain a number of endogenous enzymes, such as phosphatases and proteases, which are capable of degrading proteins in the extracts. Protein production is greatly halted and degradation is increased when proteins are extracted from cells and tissues in vitro. The best way to increase the yield of intact proteins is to add a cocktail of inhibitors of those enzymes known to be present.

This protease inhibitor cocktail contains components such as Aprotinin, Bestatin, E-64, Leupeptin with a broad specificity for cysteine, serine, acid protease and aminopeptidase. This product does not contain AEBSF, to avoid interfering with mass spectrometry (MS) analysis due to mass spectral peak drift caused by AEBSF. Therefore, protein samples extracted with this product are compatible with mass spectrometry detection. This product is supplied as a ready-to-use solution in DMSO. In addition, an additional EDTA is available for optional use.

Quality Control

Quality Control & MSDS

View current batch:
 

Components and Storage

Tube

Catalog No.

Product Name

Summary

Targets

CAS Number

Smiles

A (50X in DMSO)

A2574

Aprotinin

Bovine trypsin inhibitors

Proteases|Serine Protease

9087-70-1

 

A2575

Bestatin

Aminopeptidase inhibitors

Proteases|Aminopeptidase

58970-76-6

CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O

A2576

E-64

Cysteine protease inhibitors

Proteases|Cathepsin

66701-25-5

CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O

A2570

Leupeptin

Serine and cysteine protease inhibitors

Proteases|Serine Protease

103476-89-7

O=C(C(C([H])([H])C(C([H])([H])[H])([H])C([H])([H])[H])([H])N([H])C(C([H])([H])[H])=O)N([H])C(C(N([H])C(C([H])=O)([H])C([H])([H])C([H])([H])C([H])([H])/N=C(N([H])[H])/N([H])[H])=O)([H])C([H])([H])C(C([H])([H])[H])([H])C([H])([H])[H]

B (50X in ddH2O)

 

EDTA, disodium salt, dihydrate

Metalloproteinase inhibitors

Proteases | Metalloprotease

6381-92-6

 

Store at -20 °C for one year.