IκB/IKK
IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.
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A4210 Bay 11-7821 (BAY 11-7082)1 CitationSummary: IKK/NF-κB/TNFα inhibitor -
A4217 QNZ (EVP4593)4 CitationSummary: Potent NF-κB inhibitor -
A3230 Bay 65-1942 HCl saltSummary: IKKβ kinase inhibitor -
A3248 BMS345541 hydrochlorideTarget: IKKSummary: IKK inhibitor,highly selective -
B4655 BMS-345541(free base)Summary: IKK-1/IKK-2 inhibitor,potent and selective -
B5543 PF 184Summary: IKKβ inhibitor -
B5638 ACHPSummary: IκB kinase inhibitor -
B7683 PS 1145 dihydrochlorideSummary: IκB kinase (IKK) inhibitor -
A3308 Choline FenofibrateSummary: Choline salt of fenofibric acid -
A3311 CID-2858522Summary: NF-κB pathway inhibitor