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IκB/IKK

IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.

B1587 IMD 0354
1 Citation

Summary: IKKβ inhibitor

insoluble in H2O; ≥100.8 mg/mL
B1643 Sodium 4-Aminosalicylate

Summary: NF-κB inhibitor

≥10.65 mg/mL
N1672 Honokiol

Summary: Antioxidant/antitumor/antiangiogenic agent

insoluble in H2O; ≥83 mg/mL
N1831 Luteolin

Target: AP-1|MMP|15-lipoxygenases

Summary: Antioxidant and free radical scavenger
N1846 Tanshinone IIA

Target: AP-1|MAGL

Summary: Antioxidant and anti-inflammatory reagent

insoluble in EtOH; insoluble in H2O; ≥3.42 mg/mL
N1855 Andrographolide

Summary: NF-κB signaling Inhibitor

insoluble in EtOH; insoluble in H2O; ≥16 mg/mL
N2131 Wedelolactone

Summary: IKK inhibitor

insoluble in EtOH; insoluble in H2O; ≥44.4 mg/mL
N2031 Piceatannol

Summary: p56lck/Syk inhibitor

insoluble in H2O; ≥12.2 mg/mL
B4655 BMS-345541(free base)

Summary: IKK-1/IKK-2 inhibitor,potent and selective

insoluble in H2O; ≥70 mg/mL
B5543 PF 184

Summary: IKKβ inhibitor

<61.91 mg/mL