IκB/IKK - Inflammatory Diseases
IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.
- B1587 IMD 03541 CitationSummary: IKKβ inhibitor
- B1585 SC-514Summary: ATP-competitive IKK-2 inhibitor, orally active
- A2604 CelastrolTarget: ProteasomeSummary: Antioxidant, anti-inflammatory and immunosuppressive agent
- N1846 Tanshinone IIATarget: AP-1|MAGLSummary: Antioxidant and anti-inflammatory reagent