IκB/IKK
IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.
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N2031 PiceatannolSummary: p56lck/Syk inhibitor -
A4602 TPCA-12 CitationSummary: IKK-2 inhibitor,potent and selective -
B3033 Bay 11-70851 CitationSummary: NK-κB activation inhibitor -
B1585 SC-514Summary: ATP-competitive IKK-2 inhibitor, orally active -
B1586 IKK-16 (IKK Inhibitor VII)1 CitationSummary: Selective IκB kinase inhibitor