IκB/IKK
IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.
- A3392 EmodinTarget: CK2Summary: Naturally occurring anthraquinone,antiproliferative
- A3485 IKK-2 inhibitor VIII2 CitationSummary: IKK-2 inhibitor,potent and selective
- A3486 IKK-3 InhibitorSummary: IKK-3 Inhibitor
- A3628 MLN120BSummary: IκB Kinase β Inhibitor
- A3635 MRT67307 HClTarget: TBK1|MARK1|NUAK1Summary: SIK/TBK-1/IKKe inhibitor
- N1672 HonokiolSummary: Antioxidant/antitumor/antiangiogenic agent
- N1831 LuteolinTarget: AP-1|MMP|15-lipoxygenasesSummary: Antioxidant and free radical scavenger
- N1846 Tanshinone IIATarget: AP-1|MAGLSummary: Antioxidant and anti-inflammatory reagent
- N1855 AndrographolideSummary: NF-κB signaling Inhibitor
- N2131 WedelolactoneSummary: IKK inhibitor