IKK-2 inhibitor VIII
Catalog No.
A3485
IKK-2 inhibitor,potent and selective
Featured Products
IKK-2 inhibitor VIII is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM.
- 1. Eric M. Burton, Davide Maestri, et al. "Epstein-Barr virus latent membrane protein 1 subverts IMPDH pathways to drive B-cell oncometabolism." PLoS Pathog. 2025 May 14;21(5):e1013092. PMID: 40367275
- 2. Wang C, Jiang S, et al. "Genome-wide CRISPR-based gene knockout screens reveal cellular factors and pathways essential for nasopharyngeal carcinoma." J Biol Chem. 2019 Jun 21;294(25):9734-9745. PMID:31073033
| Storage | Store at -20°C |
| M.Wt | 400.9 |
| Cas No. | 406209-26-5 |
| Formula | C21H25ClN4O2 |
| Synonyms | IKK-beta inhibitor |
| Solubility | Soluble in DMSO |
| Chemical Name | (6E)-2-amino-6-[2-(cyclopropylmethoxy)-6-oxocyclohexa-2,4-dien-1-ylidene]-4-piperidin-4-yl-1H-pyridine-3-carbonitrile hydrochloride |
| SDF | Download SDF |
| Canonical SMILES | C1CC1COC2=CC=CC(=O)C2=C3C=C(C(=C(N3)N)C#N)C4CCNCC4.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
Related Biological Data
