Cannabinoid Receptor
The cannabinoid receptor (CB1 and CB2) is a member of G-protein coupled receptor which plays a significant role in physiologic processes such as cognitive and immune functions.
" to show IC50
to view the IC50 value.- Cat.No. Product Name Information
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B1428
GW842166X
GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase 2.
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B1427
AM251
AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain.
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B1425
BML-190
BML-190(IMMA) is a potent and selective CB2 receptor ligand (Ki values are 435 nM and > 2 μM for CB2 and CB1 respectively).
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B1429
Rimonabant
Rimonabant (SR141716) is a potent and selective antagonist of central cannabinoid (CB1) receptor with Ki values of 1.8nM and 514nM for CB1 and CB2, respectively .
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B1426
Org 27569
Org 27569 is an allosteric ligand of the cannabinoid receptor CB1.
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A1435
CP-945598 HCl
CP 945598 hydrochloride is a selective and high affinity CB1 antagonist with Ki value of 0.7 and 0.12 nM for binding and functional assays, respectively [1].
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A5827
AM1241
IC50: AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. [1].
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A3858
Taranabant
Taranabant
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A3766
Rimonabant hydrochloride
Rimonabant hydrochloride
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A3691
Otenabant
Otenabant (CP-945,598) is a recently discovered selective, high affinity, competitive CB1 receptor antagonist that inhibits both basal and cannabinoid agonist-mediated CB1 receptor signaling.
