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Related Antibodies

MDL 28170

selective inhibitor of calpain and cathepsin B

MDL 28170

Catalog No. A4412
Size Price Stock Qty
10mg $74.00 Ship Within 5 Days

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Sample solution is provided at 25 µL, 10mM.

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Quality Control & MSDS

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Chemical structure

MDL 28170

Biological Activity

Potent, selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25 nM respectively) that does not inhibit trypsin-like serine proteases.
Targets calpain cathepsin B        
IC50 10nM 25nM        

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Chemical Properties

Cas No. 88191-84-8 SDF Download SDF
Chemical Name benzyl N-[(2S)-3-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]butan-2-yl]carbamate
Canonical SMILES CC(C)C(C(=O)NC(CC1=CC=CC=C1)C=O)NC(=O)OCC2=CC=CC=C2
Formula C22H26N2O4 M.Wt 382.45
Solubility Soluble in DMSO Storage Store at -20°C
Shipping Condition: Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

Potent, selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25 nM respectively) that does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo.