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Signaling Pathways

10 Items

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  1. 2-HBA
    C3234 2-HBA
    Summary: indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
      ≤14 mg/mL
  2. CDDO-TFEA
    C4354 CDDO-TFEA
    Summary: Nrf2 activator
      ≤5 mg/mL
  3. Sulforaphane
    C4733 Sulforaphane
    Summary: inducer of chemopreventative enzymes via Keap1-Nrf2 signaling
      ≥51.6 mg/mL
  4. NK 252
    C5715 NK 252
    Summary: Nrf2 activator
      ≤14 mg/mL
  5. Dimethyl Fumarate
    B1931 Dimethyl Fumarate
    Summary: nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator
  6. Dimethylfraxetin
    N2285 Dimethylfraxetin
      ≥73.1 mg/mL
  7. 5,7-dihydroxychromone
    N2172 5,7-dihydroxychromone
     1 Citation
    Target: Nrf2/ARE signal|PPAR
    Summary: Nrf2/ARE signal activator and PPARγ agonist
  8. Omaveloxolone (RTA-408)
    B3576 Omaveloxolone (RTA-408)
    Target: Nrf2
    Summary: Nrf2 activator
      ≥55.5 mg/mL
  9. Bardoxolone
    A3220 Bardoxolone
    Target: COX|iNOS
    Summary: Once-a-day treatment for CKD
      ≥49.2 mg/mL
  10. Curcumin
    A3335 Curcumin
     1 Citation
    Target: Histone Deacetylases (HDACs)|Nrf2|Histone Acetyltransferases (HATs)|Tyrosinases
    Summary: Tyrosinase inhibitor
      ≥36.8 mg/mL

10 Items

per page