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Signaling Pathways

Signaling Pathways

A3479 Hydroxyfasudil hydrochloride

Summary: Rho-kinase inhibitor and vasodilator

insoluble in EtOH; ≥7.88 mg/mL
A3545 LDN193189 Hydrochloride
1 Citation

Summary: ALK inhibitor,potent and selective

≥27.6 mg/mL
A3642 Narciclasine

Summary: Modulates the Rho/ROCK/LIM kinase/cofilin pathway

≥14.7 mg/mL
A3658 NG25

Summary: TAK1 inhibitor

insoluble in EtOH; insoluble in H2O; ≥18.8 mg/mL
A3660 Nilotinib monohydrochloride monohydrate

Summary: Bcr-Abl inhibitor

≥50 mg/mL
A3754 RepSox

Summary: ALK5 inhibitor,potent and selective

insoluble in H2O; ≥14.35 mg/mL
A3771 RKI-1447

Target: ROCK

Summary: Potent ROCK1/ROCK2 inhibitor

insoluble in H2O; ≥16.3 mg/mL
A3799 SB-505124 hydrochloride

Target: ALK

Summary: ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
A3808 SD-208

Summary: TGF-βR I kinase inhibitor

≥8.95 mg/mL
A3825 SLx-2119
1 Citation

Target: ROCK

Summary: Selective ROCK2 inhibitor

≥22.65 mg/mL