Nilotinib monohydrochloride monohydrate
Catalog No.
A3660
Bcr-Abl inhibitor
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Nilotinib is a inhibitor of BCR-ABL, IC50 < 30nM; for the treatment of chronic myelogenous leukemia.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 583.99 |
| Cas No. | 923288-90-8 |
| Formula | C28H25ClF3N7O2 |
| Synonyms | AMN-107; Tasigna; AMN107 |
| Solubility | ≥50 mg/mL in EtOH with gentle warming; insoluble in H2O; ≥210.8 mg/mL in DMSO |
| Chemical Name | 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide;hydrate;hydrochloride |
| Canonical SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5.O.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
Related Biological Data
Related Biological Data
