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NG25

Catalog No.
A3658
TAK1 inhibitor
Grouped product items
SizePriceStock Qty
5mg
$286.00
In stock
10mg
$511.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

NG25, a TAK1 inhibitor, inhibited the activation of IKK by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells.

Chemical Properties

StorageStore at -20°C
M.Wt537.58
Cas No.1315355-93-1
FormulaC29H30F3N5O2
SynonymsNG 25;NG-25
Solubilityinsoluble in EtOH; insoluble in H2O; ≥18.8 mg/mL in DMSO
Chemical NameN-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide
SDFDownload SDF
Canonical SMILESCCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control