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Signaling Pathways

Signaling Pathways

A3008 Y-27632 dihydrochloride
19 Citation

Target: ROCK

Summary: ROCK1 inhibitor

≥111.2 mg/mL
A3310 chroman 1
1 Citation

Summary: ROCK II inhibitor, highly potent and selective

≥50.3 mg/mL
A3478 Hydroxyfasudil

Target: ROCK|Rho-kinase

Summary: Rho-kinase inhibitor and vasodilator

Soluble in DMSO
A3479 Hydroxyfasudil hydrochloride

Summary: Rho-kinase inhibitor and vasodilator

insoluble in EtOH; ≥7.88 mg/mL
A3642 Narciclasine

Summary: Modulates the Rho/ROCK/LIM kinase/cofilin pathway

≥14.7 mg/mL
A3771 RKI-1447

Target: ROCK

Summary: Potent ROCK1/ROCK2 inhibitor

insoluble in H2O; ≥16.3 mg/mL
A3825 SLx-2119
1 Citation

Target: ROCK

Summary: Selective ROCK2 inhibitor

≥22.65 mg/mL
B5863 LX7101 HCL

Summary: Dual LIM-kinase and ROCK inhibitor

insoluble in H2O; insoluble in EtOH; insoluble in DMSO
B3392 GSK269962A

Target: ROCK|RSK|MSK

Summary: ROCK inhibitor

Soluble in DMSO
B1176 Y-39983 dihydrochloride

Summary: ROCK family inhibitor

≥18.05 mg/mL