Sodium Orthovanadate
Catalog No.
A8524
PTP inhibitor
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Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Sodium orthovanadate is a commonly used general inhibitor for PTP (protein tyrosine phosphatases), alkaline phosphatase (ALP) and ATPase. Na3VO4 acts as a competitive inhibitor and is completely reversible upon the addition of EDTA or by dilution. The PTP activities are conveniently separable from the protein phosphoseryl and phosphothreonyl phosphatase (PSP) activities inhibited by Fluoride and EDTA. Vanadate is routinely used to preserve the protein tyrosyl phosphorylation state in cells, cell lysates, and protein tyrosine kinase assays. Sodium Orthovanadate is an inhibitor of AK and PFK.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 183.91 |
| Cas No. | 13721-39-6 |
| Formula | Na3O4V |
| Solubility | insoluble in DMSO; insoluble in EtOH; ≥6.7 mg/mL in H2O |
| Chemical Name | trisodium;trioxido(oxo)vanadium |
| SDF | Download SDF |
| Canonical SMILES | [O-][V](=O)([O-])[O-].[Na+].[Na+].[Na+] |
| Shipping Condition | Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request. |
| General tips | For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
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