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PI3K

PI3K (phosphatidylinositol-4,5-bisphosphate 3-kinase) is a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

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  1. CAL-101 (Idelalisib, GS-1101)
    A3005 CAL-101 (Idelalisib, GS-1101)
     2 Citation
    Target: PI3K
    Summary: PI3K inhibitor
  2. BKM120
    A3015 BKM120
     1 Citation
    Target: PI3K
    Summary: Inhibitor of pan-Class I PI3K
      ≥20.52 mg/mL
  3. CUDC-907
    A4097 CUDC-907
    Target: Histone Deacetylases (HDACs)|PI3K
    Summary: Potent PI3K/HDAC inhibitor
      ≥25.45 mg/mL
  4. BEZ235 Tosylate
    A3238 BEZ235 Tosylate
     1 Citation
    Summary: MTOR/P13K inhibitor
      Soluble in DMSO
  5. CAL-130 Hydrochloride
    A3268 CAL-130 Hydrochloride
    Summary: PI3K inhibitor
      Soluble in DMSO
  6. CZC24832
    A3340 CZC24832
    Summary: Selective PI3K-γ inhibitor
      insoluble in H2O; insoluble in EtOH; ≥6.07 mg/mL
  7. GDC-0941 dimethanesulfonate
    A3432 GDC-0941 dimethanesulfonate
    Summary: PI3K inhibitor
      insoluble in H2O; insoluble in EtOH; ≥207.6 mg/mL
  8. NVP-BKM120 Hydrochloride
    A3674 NVP-BKM120 Hydrochloride
    Summary: PI3K inhibitor
      ≥44.7 mg/mL
  9. PI-103 Hydrochloride
    A3724 PI-103 Hydrochloride
    Target: PI3K|mTOR|DNA-PK
    Summary: DNA-PK/PI 3-kinase/mTOR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥19.25 mg/mL
  10. VS-5584 (SB2343)
    A3927 VS-5584 (SB2343)
    Target: PI3K|mTOR
    Summary: MTOR/P13K inhibitor,potent and selective
      insoluble in H2O; ≥17.7 mg/mL

Items 1-10 of 62

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