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Microtubule/Tubulin

Biochemicals

  1. Cat.No. Product Name Information
  2. A3128 7-xylosyltaxol taxol (Paclitaxel) derivative
  3. B4757 INH6 INH6 is a potent Hec1 inhibitor, which specifically disrupts the Hec1/Nek2 interaction and causes chromosome mis-alignment.
  4. B3387 Eribulin Eribulin (E7389; ER-086526), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules.
  5. B3386 Eribulin mesylate Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules.
  6. B1634 Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium Combretastatin A-4 phosphate (fosbretabulin) is a microtubule destabilizing drug, a type of vascular-targeting agent, a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis.
  7. B1320 Cys-mcMMAD Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
  8. B2157 Cabazitaxel Cabazitaxel(XRP6258; RPR-116258A) is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
  9. B2298 Plinabulin (NPI-2358) vascular disrupting agent (VDA) and tubulin-depolymerizing inhibitor
  10. A1623 Epothilone A macrolide antitumor agent
  11. A1630 Epothilone B (EPO906, Patupilone) macrolide antitumor agent
  12. A3910 Vc-MMAD antibody drug conjugate.
  13. A3731 Podophyllotoxin Podophyllotoxin
  14. A3394 Epothilone D natural polyketide compound isolated from the myxobacterium Sorangium cellulosum.
  15. A3370 Docetaxel Trihydrate Docetaxel Trihydrate
  16. A3344 D-64131 D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-Tubulin. D-64131 is cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM).
  17. A3324 Colchicine Colchicine, a tubulin Inhibitor, has been shown to block polymerization of microtubules by binding to tubulin (IC50 = 3.2 μM).
  18. B7788 MPC 6827 hydrochloride Microtubule Inhibitor
  19. B6986 Flutax 1 New Product
  20. A3631 Monomethyl auristatin E Antimitotic agent
  21. A3630 MMAD Potent tubulin inhibitor
  22. A3590 Mc-MMAD Potent tubulin inhibitor
  23. B3680 Griseofulvin
  24. B1636 Vinflunine Tartrate Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity. Phase 2/3.
  25. B1635 CYT997 (Lexibulin) CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. Phase 1/2.
  26. B1035 Dolastatin 10 Dolastatin 10 is an antitumor agent .
  27. B3062 CW069 CW069 is an allosteric, and selective inhibitor of microtubule motor protein HSET with IC50 of 75 μM, significant selectivity over KSP.
  28. B3058 CK-636 CK-636 is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.
  29. B3526 Vintafolide
  30. B1136 Nemorubicin anticancer drug