Related Biochemicals Related Antibodies
Sample solution is provided at 25 µL, 10mM.
|E-64-c is an effective synthetic calpain inhibitor composed from E-64, which also inhibits cathepsin B, cathepsin H, and cathepsin L (cysteine proteases).|
|Targets||cathepsins B||cathepsins H||cathepsins L|
|Cas No.||76684-89-4||SDF||Download SDF|
|Chemical Name||(2S,3S)-3-[[(2S)-4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid|
|Solubility||Soluble in DMSO||Storage||Store at -20°C|
|Shipping Condition:||Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
E-64-c is an effective synthetic calpain inhibitor composed from E-64, which also inhibits cathepsin B, cathepsin H, and cathepsin L (cysteine proteases). The compound has been demonstrated to form a complex with papain by binding via a thioether covalent bond. Studies indicate that E-64-c, also known as Ep-475, is a more potent inhibitor of cathepsins B and L compared to E-64. Mouse lymphosarcoma LS studies show that Ep-475 decreases the effects of cyclophosphamide.