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Signaling Pathways

Items 21-30 of 225

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  1. MIM1
    A4465 MIM1
     1 Citation
    Target: Mcl-1
    Summary: Mcl-1 Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL
  2. Muristerone A
    A4466 Muristerone A
    Summary: TRAIL- and hFasL-induced apoptosis inhibitor
      Soluble in DMSO
  3. Cesium chloride
    A4468 Cesium chloride
    Summary: Potassium channel blocker
      insoluble in EtOH; insoluble in DMSO; ≥90.6 mg/mL
  4. DAPK Substrate Peptide
    A4469 DAPK Substrate Peptide
    Summary: Synthetic peptide substrate for DAPK
      Soluble to 1 mg/mL
  5. GRI 977143
    A4471 GRI 977143
    Summary: LPA2 receptor non-lipid agonist
      Soluble in DMSO
  6. Mdivi 1
    A4472 Mdivi 1
     1 Citation
    Summary: Selective DRP1/Dnm1 inhibitor, cell-permeable
      insoluble in H2O; insoluble in EtOH; ≥17.65 mg/mL
  7. NQDI 1
    A4474 NQDI 1
    Summary: ASK1, MAP3K5 inhibitor
      soluble in DMSO
  8. TLQP 21
    A4475 TLQP 21
    Summary: VGF-derived peptide
      Soluble to 1 mg/mL
  9. CP 31398 dihydrochloride
    A4476 CP 31398 dihydrochloride
    Summary: p53 stabilizer
      <43.54 mg/mL
  10. HLI 373
    A4478 HLI 373
    Summary: Hdm2 ubiquitin ligase (E3) inhibitor
      <37.79 mg/mL

Items 21-30 of 225

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Category
  1. Caspase31item
  2. 14.3.3 Proteins1 item
  3. Apoptosis Inducers43item
  4. Bax6item
  5. Bcl-2 Family30item
  6. Bcl-xL8item
  7. c-RET9item
  8. IAP9item
  9. KEAP1-Nrf210item
  10. MDM213item
  11. p5338item
  12. PC-PLC4item
  13. PKD5item
  14. RasGAP (Ras- P21)1 item
  15. Survivin2item
  16. Thymidylate Synthase5item
  17. TNF-α12item
  18. Other Apoptosis7item
  19. APC1 item
  20. PD-1/PD-L1 interaction3item
  21. ASK13item
  22. PAR42item
  23. Apoptosis6item
  24. MDM-2/p531 item
Specificity
  1. Selective51item
Reversibility
  1. Reversible1 item
  2. Irreversible9item
Target
  1. Caspases14item
  2. Proteasome1 item
  3. Histone Deacetylases (HDACs)2item
  4. Inhibitor of apoptosis proteins (IAP)3item
  5. Bcl-29item
  6. Raf2item
  7. Aurora Kinases1 item
  8. Bcl-xl3item
  9. MDM22item
  10. VEGFR3item
  11. PDGFR3item
  12. c-Kit2item
  13. RET1 item
  14. Mcl-17item
  15. Thymidylate Synthase1 item
  16. Bcr-Abl1 item
  17. Nrf22item
  18. Sir2-like Family Deacetylases (Sirtuins)1 item
  19. Deubiquitinating enzymes (DUBs)1 item
  20. Aminopeptidases1 item
  21. RIP kinases1 item
  22. PD-1/PD-L1 interaction1 item
  23. Topoisomerases1 item
  24. Survivin1 item
  25. Dehydrogenase1 item
  26. Autophagy1 item
  27. Mixed lineage kinase domain-like protein (MLKL)1 item
  28. COX1 item
  29. iNOS1 item
  30. TRP Channel1 item
  31. Apoptosis Inducers1 item
  32. angiogenesis1 item
  33. c-RET1 item
  34. FPTase1 item
  35. Bfl-11 item
  36. p53-MDM2 interaction2item
  37. p537item
  38. cysteine protease1 item
  39. Nrf2/ARE signal1 item
  40. PPAR1 item
  41. HDM2 ubiquitin ligase1 item
  42. PC-PLC2item
  43. AAT1 item
  44. HIV1 item
  45. Histone Acetyltransferases (HATs)1 item
  46. Telomerases1 item
  47. Tyrosinases1 item
  48. HSP701 item
  49. Ubiquitin E3 Ligases1 item
  50. MDMX1 item
  51. p211 item
  52. DHFR1 item
  53. GARFT1 item
  54. PKD1 item
  55. MCL11 item
  56. Bcl-w1 item
  57. Bax1 item
  58. NS3/4a Proteases1 item
Reported Experiments
  1. Animal Experiments69item
  2. Cell Experiments58item
Related Disease
  1. Acute Myeloid Leukemia1 item
  2. Adrenocortical Carcinoma1 item
  3. Autoimmune Diseases1 item
  4. Breast Cancer9item
  5. Cancer46item
  6. Chronic Lymphocytic Leukemia1 item
  7. Chronic Myeloproliferative Disorders1 item
  8. Colon Cancer4item
  9. Colorectal Cancer3item
  10. Glioblastoma4item
  11. HCV1 item
  12. Hepatocellular Carcinoma1 item
  13. Inflammatory Diseases1 item
  14. Lung Cancer3item
  15. Lymphoma4item
  16. Melanoma2item
  17. Multiple Myeloma2item
  18. Myelofibrosis1 item
  19. Myeloma1 item
  20. Neuroblastoma1 item
  21. Non-small Cell Lung Cancer4item
  22. Ovarian Cancer1 item
  23. Pain Relief1 item
  24. Pancreatic Cancer3item
  25. Pentacyclic Triterpenoid1 item
  26. Prostate Cancer5item
  27. Pulmonary Fibrosis1 item
  28. Rheumatoid Arthritis1 item
  29. Soft Tissue Sarcoma1 item
  30. Testicular Cancer1 item