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GRI 977143

Catalog No.
A4471
LPA2 receptor non-lipid agonist
Grouped product items
SizePriceStock Qty
10mg
$299.00
Ship with 5-10 days
50mg
$1,229.00
Ship with 5-10 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 μM). Does not activate other LPA GPCRs at concentrations up to 10 μM. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activates ERK1/2 survival pathway.

Chemical Properties

Physical AppearanceWhite solid
StorageStore at 4°C
M.Wt391.44
Cas No.325850-81-5
FormulaC22H17NO4S
SolubilitySoluble in DMSO
Chemical Name2-[3-(1,3-dioxobenzo[de]isoquinolin-2-yl)propylsulfanyl]benzoic acid
SDFDownload SDF
Canonical SMILESC1=CC=C(C(=C1)C(=O)O)SCCCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

GRI 977143