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Signaling Pathways

Items 21-30 of 250

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  1. PHA-680632
    A4122 PHA-680632
    Target: Aurora Kinases|PLK|FGFR
    Summary: Aurora kinase inhibitor,novel and potent
      ≥50.2 mg/mL
  2. TAK-901
    A4124 TAK-901
    Target: Aurora Kinases|FLT3|Src|JAK|LRRK2|Hck|FGR|YES|Fyn|ARG
    Summary: Novel Aurora A/B inhibitor
      ≥25.25 mg/mL
  3. CYC116
    A4125 CYC116
    Target: Aurora Kinases|FLT3|VEGFR
    Summary: Potent Aurora A/B inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.4 mg/mL
  4. Aurora A Inhibitor I
    A4126 Aurora A Inhibitor I
    Target: Aurora Kinases
    Summary: Aurora A inhibitor
      ≥29.4 mg/mL
  5. GSK1070916
    A4127 GSK1070916
    Target: Aurora Kinases
    Summary: Aurora B/C inhibitor
      ≥25.4 mg/mL
  6. PF-03814735
    A4128 PF-03814735
    Target: Aurora Kinases
    Summary: Aurora A/B inhibitor
      Soluble in DMSO
  7. Paclitaxel (Taxol)
    A4393 Paclitaxel (Taxol)
     4 Citation
    Target: Microtubules/Tubulins
    Summary: Antineoplastic agent
      ≥85.6 mg/mL
  8. Docetaxel
    A4394 Docetaxel
     3 Citation
    Summary: Microtubulin disassembly inhibitor
      ≥40.4 mg/mL
  9. 10-DAB (10-Deacetylbaccatin)
    A4395 10-DAB (10-Deacetylbaccatin)
    Summary: Precursor of antitumor compound Palitaxel and Docetaxel
      ≥22.25 mg/mL
  10. 360A
    A3119 360A
    Summary: G-quadruplex structures inhibitor
      Soluble in DMSO

Items 21-30 of 250

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  1. ATM/ATR9item
  2. Aurora Kinase28item
  3. Cdc424item
  4. Cdc72item
  5. Chk15item
  6. c-Myc3item
  7. CRM14item
  8. Cyclin-Dependent Kinases65item
  9. E1 enzyme1 item
  10. G-quadruplex3item
  11. Haspin1 item
  12. HMTase1 item
  13. Kinesin7item
  14. Ksp4item
  15. Microtubule/Tubulin33item
  16. Mps13item
  17. Mitotic7item
  18. RAD513item
  19. ROCK16item
  20. Rho12item
  21. PAK14item
  22. PAK42item
  23. PERK4item
  24. PLK18item
  25. PTEN2item
  26. Wee11 item
Specificity
  1. Selective80item
Reversibility
  1. Reversible9item
  2. Irreversible2item
Target
  1. Cyclin-Dependent Kinases30item
  2. PI3K2item
  3. Aurora Kinases20item
  4. mTOR1 item
  5. FLT35item
  6. GSK-31 item
  7. PLK11item
  8. Chk8item
  9. VEGFR1 item
  10. PDGFR1 item
  11. RET1 item
  12. Bromodomain-containing proteins(BRDs)1 item
  13. MEK1 item
  14. FGFR1 item
  15. Voltage-gated Sodium (NaV) Channels1 item
  16. Src3item
  17. Microtubules/Tubulins5item
  18. ROCK10item
  19. PAK3item
  20. JAK1 item
  21. DNA-PK1 item
  22. Ksp2item
  23. PKC1 item
  24. RAD512item
  25. LRRK21 item
  26. KRAS G12C1 item
  27. PKG1 item
  28. PKA1 item
  29. Myosin light chain kinases (MLCKs)1 item
  30. Clk1 item
  31. MK21 item
  32. ATM/ATR6item
  33. Farnesyl Diphosphate Synthases1 item
  34. G-quadruplexes1 item
  35. Cdc421 item
  36. Hck1 item
  37. Arp2/3 complex1 item
  38. Cdc71 item
  39. Ubiquitin-activating Enzyme E11 item
  40. Microtubule/Tubulin3item
  41. VEGFR3/FLT41 item
  42. NTRK1/TRKA1 item
  43. CSF-1R/c-Fms1 item
  44. nuclear export1 item
  45. CRM11 item
  46. Hec11 item
  47. Histone Acetyltransferases (HATs)1 item
  48. Rho1 item
  49. Lck1 item
  50. FGR1 item
  51. YES1 item
  52. Fyn1 item
  53. ARG1 item
  54. Rho-kinase1 item
  55. ATM1 item
  56. PTEN1 item
Reported Experiments
  1. Animal Experiments88item
  2. Cell Experiments71item
Related Disease
  1. Acute Myeloid Leukemia7item
  2. B-lymphoid Malignancies1 item
  3. Breast Cancer16item
  4. Cancer77item
  5. Cervical Cancer1 item
  6. Chronic Lymphocytic Leukemia2item
  7. Colon Cancer10item
  8. Colon Carcinoma1 item
  9. Colorectal Cancer5item
  10. Glioblastoma2item
  11. Glioma2item
  12. Leukemia1 item
  13. Liver Cancer1 item
  14. Lung Cancer7item
  15. Lymphoma4item
  16. Mantle Cell Lymphoma1 item
  17. Melanoma2item
  18. Multiple Myeloma1 item
  19. Neuroblastoma1 item
  20. Non-small Cell Lung Carcinoma1 item
  21. Ovarian Cancer10item
  22. Pancreatic Cancer7item
  23. Prostate Cancer5item
  24. Renal Cell Carcinoma1 item
  25. Thyroid Cancer1 item