Pseudo-UTP
Catalog No.
B7972
Pseudo-modified uridine triphosphate, can replace UTP for in vitro mRNA transcription synthesis.
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Pseudo-UTP is a nucleoside triphosphate analogue in which the uracil base is replaced by pseudouracil (pseudouridine). Pseudouridine is a naturally occurring nucleotide modification widely present in various RNA molecules. In vitro transcription reactions can utilize pseudo-UTP instead of UTP to produce RNA molecules containing pseudouridine modifications, enhancing RNA stability and functionality, and thus increasing their persistence within cells. Incorporation of pseudouridine can also enhance RNA translation efficiency and reduce immunogenicity, making it highly valuable for mRNA vaccine development and gene therapy applications.
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| Storage | Store at -20°C or below |
| M.Wt | 484.1 (free acid) |
| Cas No. | 1175-34-4 |
| Formula | C9H15N2O15P3 (free acid) |
| Chemical Name | lithium (5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | O=C(NC=C1C2C(O)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)NC1=O.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.73% by AX-HPLC
- COA (Certificate Of Analysis)
- HPLC
- MS (Mass Spectrometry)
- MSDS (Material Safety Data Sheet)
Chemical structure
Related Biological Data
