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L-Glutathione Reduced

Catalog No.
B7775
An endogenous antioxidant
Grouped product items
SizePriceStock Qty
10mM (in 1mL H2O)
$61.00
In stock
5g
$55.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

L-Glutathione Reduced (CAS 70-18-8) is an endogenous thiol-containing tripeptide antioxidant found ubiquitously in living cells. It exerts biological effects primarily by scavenging reactive oxygen species (ROS) and maintaining the redox balance within cells. By neutralizing oxygen radicals and regenerating other antioxidants, including vitamin E and ascorbic acid, it mitigates oxidative stress implicated in conditions such as cancer, cardiovascular diseases, and inflammation. In biomedical research, L-Glutathione Reduced also serves as a substrate for glutathione S-transferase (GST) affinity purification methods and as a biomarker in oxidative stress studies.

Product Citation

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt307.32
Cas No.70-18-8
FormulaC10H17N3O6S
Solubilityinsoluble in EtOH; insoluble in DMSO; ≥14.25 mg/mL in H2O
Chemical Name(S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-5-oxopentanoic acid
SDFDownload SDF
Canonical SMILESSC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Protocol

Animal experiment [1]:

Animal models

Male Hypothyroidism Wistar rats

Dosage form

0.0012%, oral administration

Application

Compared with the control group, no significant effects were observed in the rates of lipid peroxidation and vitamin E in hepatic and cardiac tissues of hypothyroidism rats, while the thyroid function of hyperthyroidism rats was significantly enhanced.

Other notes

Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.

References:

[1]. Messarah M, Boulakoud MS, Boumendjel A, Abdennour C, El Feki A. The impact of thyroid activity variations on some oxidizing-stress parameters in rats. C R Biol. 2007 Feb;330(2):107-12. Epub 2006 Dec 12. PubMed PMID: 17303537.

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