7-Deaza-ATP
Catalog No.
B8040
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7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom. This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins. As a nucleotide analog, 7-Deaza-ATP can be incorporated into DNA and RNA strands, thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis, replication, and repair processes. Due to these properties, this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes, facilitating research towards nucleotide-targeted therapeutic strategies.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 506.19 (free acid) |
| Formula | C11H17N4O13P3 (free acid) |
| Synonyms | 7-Deazaadenosine-5'-Triphosphate |
| Chemical Name | lithium (5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | NC1=NC=NC2=C1C=CN2C3C(O)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O3.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity ≥90% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
