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TC-A 2317 hydrochloride

Catalog No.
Aurora kinase A inhibitor,potent and selective
Grouped product items
SizePriceStock Qty
Ship with 5-10 days
Ship with 5-10 days

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Potent Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50 values > 1000 nM). Exhibits good cell permeability and antitumor activity.

Chemical Properties

Physical AppearancePale yellow solid
StorageStore at 4°C
Cas No.1245907-03-2
Solubility<39.29mg/ml in DMSO; <19.65mg/ml in ethanol
Chemical Name6-((3-isocyano-4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyridin-2-yl)amino)-2-methylheptan-2-ol hydrochloride
SDFDownload SDF
Canonical SMILESCC(CCCC(C)(C)O)NC1=NC(NC2=NNC(C)=C2)=CC(C)=C1[N+]#[C-].Cl
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

TC-A 2317 hydrochloride